Miguel was involved in both the chemistry and the biology side of our research. In addition to the development of zinc-sensitive fluorescent indicators, he studied the substrate tolerability of a protein tag called "SNAP-tag", and developed a two-step labeling strategy that combines the powers of protein tag and bioorthogonal chemistry. Miguel now is a Postdoctoral Fellow to continue research in chemical biology in the Beatty Group in the Oregon Health and Science University in Portland.
Now a graduate student in Hedi Mattoussi's group
Neda stayed briefly in the Zhu Group. She started the research on a class of excited-state intramolecular proton transfer compounds with the opposite solvent dependency from what was expected. She is now a graduate student in the Mattoussi group.
Quinton made major contributions to the studies on fluorophores possessing intramolecular hydrogen bonds. He was also the photographer of the group, and won an image award from the Chemical and Engineering News. Quinton took a year sabbatical at Argonne National Laboratory to participate in research on lithium-ion batteries. After graduation, Quinton returned to Argonne as a Postdoctoral Fellow to resume his research in the area of energy storage.
Kirsten developed fluorescent indicators for zinc ions and hydrogen peroxide. She also applied her indicators in illuminating zinc and hydrogen peroxide in living cells using fluorescence microscopes. Kirsten was an Assistant Professor of Chemistry at Tennessee Wesleyan University. She is currently a Lecturer at North Carolina State University.
Tyler worked on the coordination chemistry of 1,2,3-triazoles and its application in developing zinc-sensitive fluorescent indicators. He also made significant contributions to the mechanistic work on copper(II) acetate mediated azide-alkyne cycloaddition reactions. Tyler is now the Chair of the Division of Science and Health at Enterprise State Community College in Enterprise, Alabama.
Heather studied triazolyl-containing multidentate ligands as zinc-sensitive fluorescent indicators. She contributed to our work in copper(II) acetate-mediated azide-alkyne cycloaddition chemistry, in particular, the effect of ligands in the efficiency of this reaction, and the 5-iodotriazole synthesis. She also cleverly demonstrated the synthetic utility of 5-iodotriazole in producing polyheterocyclic organic molecules. Heather is a Principal Investigator at Smart Biomolecules, Inc. in Port Saint Lucie, Florida.
Wendy discovered the high reactivity of chelating azides in copper-catalyzed azide-alkyne cycloaddition reaction. This work has been applied by many in need of a rapid version of this reaction. She also reported a new, rather convenient method to make 5'-iodotriazole from terminal alkyne and organic azide. Wendy was a professor at Tennessee Wesleyan University. She is now a Laboratory Coordinator at Alltech in Kentucky.